Heart Allograft Tolerance Induced and Maintained by Vascularized Hind-Limb Transplant in Rats
Organ/tissue transplantation has become an effective therapy for end-stage diseases.However, immunosuppression after transplantation may cause severe side effects.Donor-specific transplant tolerance was proposed to solve this problem.In this study, we report a novel method for inducing and maintaining heart allograft tolerance Mocassino rats.First,